Abstract

Case Report

Liver cyst infection in kidney transplant patient with autosomal dominant polycystic kidney disease: Interest of PET/CT in diagnosis and treatment

Georgery H*, Migali G, Pochet JM, Tintillier M, Van Ende C and Cuvelier C

Published: 14 December, 2018 | Volume 2 - Issue 3 | Pages: 053-056

Liver cyst infection in patients with autosomal dominant polycystic kidney disease (ADPKD) is a rare but life-threatening complication. Diagnosis and treatment remain challenging. We report the case of a 64-year-old kidney transplant patient presenting with fever and abdominal pain. The diagnosis of liver cyst infection was made by positron emission tomography scan (PET/CT). Moreover, the course of our patient illustrates the interest of subsequent PET/CT during follow-up as our patient failed on antibiotherapy and required liver cyst drainage.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001019 Cite this Article Read Full Article PDF

Keywords:

ADPKD; Kidney transplant; Liver cyst infection; Treatment; CA19-9; PET/CT

References

  1. Gall TM, Oniscu GC, Madhavan K, Parks RW, Garden OJ. Surgical management and longterm follow‐up of non‐parasitic hepatic cysts. HBP (Oxford). 2009; 11: 235-241. Ref.: https://goo.gl/nXsEUK
  2. Pirson Y, Kanaan N. Complications infectieuses associées à la polykystose rénale autosomique dominante. Nephrol ther. 2015; 11: 73-77. Ref.: https://goo.gl/7XVxEt
  3. Lantinga MA, Geudens A, Gevers TJG, Drenth JPH. Systematic review: the management of hepatic cyst infection. Aliment Pharmacol Ther. 2015; 41: 253–261. Ref.: https://goo.gl/B33yyd
  4. Sallee M, Rafat C, Zahar JR, Paulmier B, Grunfeld JP, et al. Cyst infections in patients with Autosomal Dominant Polycystic Kidney Disease. Clin J Am Soc Nephrol. 2009; 4: 1183-1189. Ref.: https://goo.gl/UKhJVJ
  5. Lantinga MA, De Sevaux RG, Drenth JP. 18F-FDG PET/CT during diagnosis and followup of recurrent hepatic cyst infection in autosomal dominant polycystic kidney disease. Clin Nephrol. 2015; 84: 61–64. Ref.: https://goo.gl/4JUrij
  6. Neuville M, Hustinx R, Jacques J, Krzesinski JM, Jouret F. Diagnostic Algorithm in the Management of Acute Febrile Abdomen in Patients with Autosomal Dominant Polycystic Kidney Disease. PLoS ONE. 2016; 11: e0161277. Ref.: https://goo.gl/zbGgUP
  7. Fukasawa H, Kaneko M, Niwa H, Yasuda H, Kumagai H, et al. Carbohydrate antigen 19-9 is significantly elevated in autosomal dominant polycystic kidney disease. Nephrology (Carlton). 2018; 23: 210-216. Ref.: https://goo.gl/awzFJ6
  8. Lantiga MA, Drenth JP, Gevers TJ. Diagnostic criteria in renal and hepatic cyst infection. Nephrology Dialysis Transplantation. 2015; 30: 744-7451. Ref.: https://goo.gl/p5Qjj4
  9. Chapman AB, Devuyst O, Eckardt KU, Gansevoort RT, Harris T, et al. Autosomal Dominant Polycystic Kidney Disease (ADPKD): Executive Summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney international. 2015; 88: 17-27. Ref.: https://goo.gl/RtcfYY
  10. Suwabe T, Araoka H, Ubara Y, Kikuchi K, Hazue R, et al. Cyst infection in autosomal dominant polycystic kidney disease: causative microorganisms and susceptibility to lipidsoluble antibiotics. Eur J Clin Microbiol Infect Dis. 2015; 34: 1369–1379. Ref.: https://goo.gl/yd4XSB
  11. Pirson Y, Chauveau D, Devuyst O. Autosomal dominant polycystic kidney disease. In: Davidson AM, editor. Oxford textbook of clinical nephrology. 3rd ed, Oxford: Oxford University Press. 2005; 2304-24.

Figures:

Figure 1

Figure 1

Similar Articles

Recently Viewed

  • Peripheral perfusion index in critically ill COVID-19 and its association with multiorgan dysfunction
    Cornu Matias German*, Tonelier Matias, Roel Pedro, Sanhueza Laura, Orozco Sergio Martin, Sepulveda Mariana Elizabet, Svampa Silvana Enrica and Arana Osorio Erick and Martinuzzi Andres Luciano Nicolas Cornu Matias German*, Tonelier Matias, Roel Pedro, Sanhueza Laura, Orozco Sergio Martin, Sepulveda Mariana Elizabet, Svampa Silvana Enrica, Arana Osorio Erick and Martinuzzi Andres Luciano Nicolas. Peripheral perfusion index in critically ill COVID-19 and its association with multiorgan dysfunction. J Clin Intensive Care Med. 2023: doi: 10.29328/journal.jcicm.1001043; 8: 004-013
  • Dalbavancin and moleculight in the COVID-19 pandemic
    Wayne J Caputo*, George Fahoury, Donald Beggs and Patricia Monterosa Wayne J Caputo*, George Fahoury, Donald Beggs, Patricia Monterosa. Dalbavancin and moleculight in the COVID-19 pandemic. J Clin Intensive Care Med. 2023: doi: 10.29328/journal.jcicm.1001042; 8: 001-003
  • Development of Latent Fingerprints Using Food Coloring Agents
    Kallu Venkatesh, Atul Kumar Dubey and Bhawna Sharma Kallu Venkatesh,Atul Kumar Dubey,Bhawna Sharma. Development of Latent Fingerprints Using Food Coloring Agents. J Forensic Sci Res. 2024: doi: 10.29328/journal.jfsr.1001070; 8: 104-107
  • Crime Scene Examination of Murder Case
    Subhash Chandra*, Pradeep KR, Jitendra P Kait, SK Gupta and Deepa Verma Subhash Chandra*,Pradeep KR,Jitendra P Kait,SK Gupta,Deepa Verma. Crime Scene Examination of Murder Case. J Forensic Sci Res. 2024: doi: 10.29328/journal.jfsr.1001071; 8: 108-110
  • Challenges and Concerns of Parents with Children with Down Syndrome
    . Challenges and Concerns of Parents with Children with Down Syndrome. Arch Psychiatr Ment Health. 2023: doi: 10.29328/journal.apmh.1001048; 7: 015-017

Read More

Most Viewed

Read More

Help ?