Abstract

Case Report

A remote cause of anuria in a child

Mehtap Çelakıl*, Zelal Ekinci and Kürşat Demir Yıldız

Published: 26 February, 2020 | Volume 4 - Issue 1 | Pages: 011-013

Acute renal injury is a rare complication of idiopathic nephrotic syndrome with mesPGN. Here we present a 2-year-old male patient with 4 days history of anuria, generalized edema and hypervolemia. Any evidence other than proteinuria and renal failure could not be identified with laboratory tests and doppler ultrasonography. Anuric presentation was thought to be related with rapidly progressive glomerulonephritis, diffuse mesangial sclerosis or acute tubular necrosis. However, renal biopsy revealed mesangial proliferative glomerulonephritis (mesPGN). Prednisolone 2 mg/kg/day was prescribed. Diuresis was started gradually and on the 10th day of disease, anuria was resolved and acute renal injury recovered without any sequel. This case is presented because of the incompatibility between clinical findings and histopathologic diagnosis. It is concluded that although rare, anuria and acute renal injury could be the presenting symptom of idiopathic nephrotic syndrome in childhood. 

Read Full Article HTML DOI: 10.29328/journal.jcn.1001050 Cite this Article Read Full Article PDF

Keywords:

Acute renal injury; Anuria; Infant; mesPGN

References

  1. Agarwal N, Phadke KD, Garg I, Alexander P. Acute renal failure in children with idiopathic nephrotic syndrome. Pediatr Nephrol. 2003; 18:1289-1292. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/14579139
  2. Sakarcan A, Timmons C, Seikaly M. Reversible idiopathic acute renal failure in children with primary nephrotic syndrome. J Pediatr. 1994: 125: 723-727. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/7965423
  3. Smith JD, Hayslett JP. Reversible renal failure in nephrotic syndrome. Am J Kidney Dis. 1992; 19: 201-213. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/1553965
  4. Ahmed M. Minimal Change Nephrotic Syndrome Presenting as Acute Renal Failure. Indian Pediatr. 2003; 40: 676-678. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/12881627
  5. Pstrusinska K, Zwolinska D, Musial K. Acute renal failure in children with idiopathic nephrotic syndrome. Pol Merkuriusz Lek 2000; 8:462-464.
  6. Bohman SO, Jaremko G, Bohlin AB, Berg U. Foot process fusion and glomerular filtration rate in minimal change nephrotic syndrome. Kidney Int. 1994; 25: 696-700. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/6482174
  7. Vande Walle J, Mauel R, Raes A, Vandekerckhove K, Donckerwolcke. ARF in children with minimal change nephrotic syndrome may be related to functional changes of the glomerular basal membrane. Am J Kidney Dis. 2004; 43: 399-404. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/14981597
  8. Mubarak M, Lanewala A, Kazi IJ, Akhter F, Sher A, et al. Histopathological spectrum of childhood nephrotic syndrome in Pakistan. Clin Exp Nephrol. 2009; 13: 589-593. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/19636666
  9. Gulati S, Sharma PA, Sharma RK, Gupta A, Gupta RK. Do current recommendations for kidney biopsy in nephrotic syndrome need modifications? Pediatr Nephrol. 2002; 17: 404-408. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/12107803
  10. Sinha A, Bagga A. Nephrotic Syndrome. Indian J Pediatr. 2012; 79: 1045-1055. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/22644544

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