Figure 1

An update in the utilization of N-acetyl cysteine & vitamin c for tackling the oxidative stress in acute kidney injury secondary to robust sepsis - A systematic review

Kulvinder Kochar Kaur*, Gautam Allahbadia and Mandeep Singh

Published: 01 February, 2022 | Volume 6 - Issue 1 | Pages: 001-018

jcn-aid1084-g001

Figure 1:

Courtesy ref no-15-Scheme of the posited association amongst sepsis- stimulated generation of reactive oxygen species (ROS) along with reactive nitrogen species (RNS) besides inflammation, tissue, in addition to vascular damage. ROS and RNS result in escalated generation of immune-modulatory cells at regions of damage in vessels as well as tubules, thus starting a complex cascade of inflammation along with damage. Significantly, tissue along with vascular damages in robust sepsis can have harmful,actions as they can aid in an uncoupling of endothelial nitric oxide synthase (eNOS), modulated endothelial impairment as well as tissue hypoxia, thereby aid in escalating the accrual of ROS and RNS.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001084 Cite this Article Read Full Article PDF

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